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Enhanced Fluorescence Signal through the Application of Aromatic Additives onto the Microscopy Sample for Standard Fluorescence, Fluorescence Microscopy, and Combined Fluorescence MALDI Microscopy/imaging

Value Proposition· Enhanced Fluorescence Intensity: Increases signal strength, enabling detection of molecules that are undetectable with traditional fluorescence microscopy and imaging techniques· Improved Efficiency: Requires less dye to achieve strong fluorescence signals and protects the sample from oxidative degradation, reducing reagent...

Published: 9/12/2025 | Inventor(s): Kristine Glunde, Ethan Yang, Caitlin Tressler, Scot Kuo, Hoku Kahele West-Foyle, Xinyi Shen

Keywords(s):

Category(s): Technology Classifications > Research Tools > Imaging, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Buffers & Media Solutions, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Medical Devices > Imaging

Photoacoustic Imaging Platform for Intraoperative Evaluation and Treatment of Peripheral Nerve Injuries

Value Proposition:Highly accurate and objective determination of nerve injury site during surgical operations.Reduces patient risk during nerve surgeries by improving upon existing rudimentary methods.Quantifies nerve regeneration potential for a prognosis of patient recovery.Accessible and mobile imaging device for intraoperative use or postoperative...

Published: 9/12/2025 | Inventor(s): Muyinatu Bell, Michelle Graham, Nicholas von Guionneau, Sami Tuffaha

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Traumatic Injury, Clinical and Disease Specializations > Surgery, Technology Classifications > Diagnostics > Prognostic Biomarkers

Method for 3D-2D Registration of Low-Contrast and/or Deformable Structures

JHU Ref #: C17165Value Proposition· Advanced Visualization – currently the only imaging registration software that can perform registration of low-contrast structures.· Enhanced Accuracy – provides precise local and global 3D-2D image registration.· Software Versatility – effective for both low-contrast and movable structures, making...

Published: 9/12/2025 | Inventor(s): Jeffrey Siewerdsen, Rohan Vijayan

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Clinical and Disease Specializations > Surgery, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis

Apparatus and Method for modular ultrasound and photoacoustic imaging and interactive guidance using a position-tracked modular imaging framework

Value Proposition· Wearable ultrasound system that is adaptable to different patient physiologies and ages.· Allows for longitudinal and non-invasive monitoring of internal organs of critical care patients.· Applicable across a broad range of organ systems and disease indications.· Simulation-aided interactive guidance simplifies...

Published: 9/12/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Ananya Tandri

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Imaging

Non-contact Ultrasound Tomography Imaging System

Multifunctional 3D ultrasound imaging systemJHU Ref #: C17859Value Proposition:· Generation of high resolution 3D images for detection and diagnosis of diseases.· Overcomes previous required use of media (water) to image.· Media-less imaging ability allows for integration of other imaging techniques (MRI, PET, CT). Unmet Need· The...

Published: 9/12/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Hyunwoo Song, Yixuan Wu

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Image-Guided Autonomous Robotic Surgical Resection System

Technology Description· Current methods for tumor resection are limited in precision and consistency. Researchers at Johns Hopkins have developed an autonomous system for tumor resection (ASTR) which consists of a pioneering dual-arm, vision-guided autonomous robotic system. ASTR integrates advanced hardware—including two six-degree-of-freedom...

Published: 9/12/2025 | Inventor(s): Axel Krieger, Jiawei Ge, Michael Kam, Ethan Kilmer, Hamed Saeidi, Justin Opfermann, Simon Leonard

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Surgery, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Computers, Electronics & Software > Robotics, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis

Improved Raman Spectroscopy and Combined Raman-MALDI Imaging Workflow with the Addition of Aromatic Compounds

Unmet NeedRaman spectroscopy is a sensitive technique that provides the overall molecular vibrational signature of a sample. Its nondestructive nature has made it possible for in vivo imaging of cells and other small organisms. Furthermore, advances in this field have made high resolution mapping, known as Raman spectroscopy imaging (RSI), possible....

Published: 9/12/2025 | Inventor(s): Kristine Glunde, Ishan Barman, Ethan Yang, Jeong Hee Kim, Caitlin Tressler

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging

Automatic Radiological Reports and ASPECTS Calculation from Brain MRIs

Unmet NeedThe typical workflow for reporting quantitative data in Picture Archive and Communication System (PACS), is redundant, subjective, time-consuming, and hard to record. Automated radiological reports describing consistent lesion features such as location, contrast, and volumes, and related effects is a time-saver, particularly in acute conditions...

Published: 9/12/2025 | Inventor(s): Andreia Faria, Chin-Fu Liu

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Compact Capillaroscope for Non-invasive Blood Analysis

Unmet NeedAnalysis of a complete blood count (CBC) test can help detect a plethora of diseases and conditions including leukemia, anemia, and blood infections. The information gained from a CBC analysis helps doctors treat any unusual symptoms, reduce risk of disease or complications, or simply help the patient make decisions to optimize their health....

Published: 9/12/2025 | Inventor(s): Nicholas Durr, Gregory McKay

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Diagnostics > In Vivo Diagnostics, Clinical and Disease Specializations > Hematology, Technology Classifications > Medical Devices > Imaging

Photoacoustic Tumor Bed Imaging in Breast Conserving Surgery

Method for identifying residual breast cancer cells following tumor removalJHU Ref #: C17840Value Proposition· Enables medical professionals to identify residual tumor cells for removal in real-time· Reduces time and cost by eliminating need for post-operative analysis of excised tissue· Safe and radiation-free alternative to other...

Published: 9/12/2025 | Inventor(s): Emad Boctor, Russell Taylor, Laura Connolly, Gabor Fichtinger, Parvin Mousavi

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications, Technology Classifications > Medical Devices > Imaging

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