Search Results - xiaobing+he

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Three Material Decomposition using a Triple-Layer Flat-Panel Detector

Value Proposition:Method for direct, real-time visualization of bone, water, and iodine contrast agents.Allows for better visualization of moving structures; reduces imaging artifacts induced by motion (i.e. beating heart) Technology DescriptionResearchers at Johns Hopkins have developed a method for fast processing of data acquired using a triple-layer...

Published: 7/5/2024 | Inventor(s): Joseph Stayman, Jianan Gang, Xiao Jiang

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Computers, Electronics & Software > Machine Learning

Very Fast and Efficient Light-inducible CRISPR/Cas9 System for Genome Editing

Unmet NeedSince CRISPR has been proposed as a genome editing tool in 2012, it has revolutionized the field and created excitement extending beyond the genome editing scientific community. Due to its simplicity and efficiency, CRISPR-Cas9 systems have already shown promise in multiple fields, e.g., medicine, agriculture and even biofuels (through CRISPR-edited...

Published: 7/5/2024 | Inventor(s): Taekjip Ha, Yang Liu, Roger Zou, Bin Wu

Keywords(s): Discovery/Research Tools, Enzymes, Recombinant Proteins, Research Reagent

Category(s): Technology Classifications > Research Tools > Nucleic Acids

Rapid Assay for Carcinoma Stem Cells

Unmet NeedWhile cancer therapeutics have drastically improved patient outcomes in numerous indications, novel methods to prevent cancer metastasis and recurrence are needed. Cancer stem cells (CSCs) are a unique subpopulation of a tumor that are more oncogenic and slow-growing than other cancer cells within the tumor. CSCs make up approximately .1-10%...

Published: 7/4/2024 | Inventor(s): William Matsui, Xiaobing He, David Berman

Keywords(s): Antibodies, Biologics, Bladder Cancer, Cancers, Disease Indication, Immunotherapy, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Urology, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Bladder Cancer

Inhibitors of Beta Lactamase

Unmet NeedDrug resistance to antibiotics, especially β-lactam antibiotics such as penicillin, cephalosporin and related compounds is one of the most serious problems in the treatment of infectious diseases. It represents not only a significant medical problem, but a major public health and economic burden. Reports from the Center for Disease Control...

Published: 7/4/2024 | Inventor(s): Samuel Milstein, Irene Luque, Xiao Yingxin, Raphael Ottenbrite, Patrick Ross, Ernesto Freire

Keywords(s): Antagonists/Inhibitors, Bacterial Infections, Disease Indication, Infectious Diseases, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections

System for telerobotic surgery

A combined teleoperative-cooperative controllable robotic system includes a robotic actuator assembly, a control system adapted to communicate with the robotic actuator assembly, and a teleoperation unit adapted to communicate with the control system. The control system is configured to control at least a first portion of the robotic actuator assembly...

Published: 7/4/2024 | Inventor(s): Marcin Balicki, Xia Tian, Peter Kazanzides, Russell Taylor

Keywords(s): Interventional and Surgical Systems, Surgical Control Systems

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices

Electro-mechanically Stretched Micro Fibers and Methods of Use

C11956: Improved Stretched Microfiber ProductionNovelty: This technology is a new method for producing stretched microfibers with smaller, more consistent diameters.Value Proposition: While there are numerous known applications for microfibers, current fabrication methods lack a significant amount of control. These primarily consist of using a high...

Published: 7/4/2024 | Inventor(s): Hai-Quan Mao, Shuming Zhang, Xi Liu, Brian Ginn, Sharon Gerecht, Sebastian Barreto Ortiz

Keywords(s): Drug Delivery Vehicle, Hydrogel, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities

Chemical Control of Trk Signaling in Mice

C04844: Chemical Control of Trk Signaling in Mice Technical Details: Neurotrophins are a family of molecules that encourage survival of nervous tissue by secreting factors in a neuron's target field, and act by prohibiting the neuron from apoptosis. The neurotrophin family include nerve growth factors nerve growth factor (NGF), Brain-derived...

Published: 7/4/2024 | Inventor(s): David Ginty, Xi Chen

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, Growth Factors, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model, Recombinant Proteins, Research Reagent

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools