Search Results - adeno+virus

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DPL: Packaging Cell Line For Diphtheria Toxin Expressing Non-replicating Adenovirus

The invention provides a packaging cell line for production of diphtheria toxin (DT) expressing, non-replicating adenovirus for use in suicide gene therapy of cancer cells, as well as production of immunotoxins. Also provided are methods for producing diphtheria toxin (DT) expressing, non-replicating adenovirus, methods for producing immunotoxins, and...

Published: 3/13/2025 | Inventor(s): Wasim Chowdhury, Ronald Rodriguez

Keywords(s): Adeno Virus, Biologics, Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, Infectious Diseases, Polypeptide, Research Reagent, Therapeutic Matter, Therapeutic Substance, Therapeutics, Translational Research Biomarker, Viruses

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools > Viruses, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Peptides

Cell Line 2V6.11

C10340: Cell Line 2V6.11 Technical Details: The human adenovirus E4 ORF 6 34 kDa oncoprotein (E4 34k), in concert with the 55 kDa product of E1b, prevents concatenation of viral genomes in infected cells, inhibits the repair of double strand breaks (DSBs) in the viral genome, and inhibits V(D)J recombination in a plasmid transfection assay. These...

Published: 3/13/2025 | Inventor(s): Elizabeth Ketner, Gary Ketner

Keywords(s): Adeno Virus, Basic Research Biomarker, Cell Lines, Discovery/Research Tools, Human Cell Lines, In Vitro Research Tool, Research Reagent, Viruses

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools > Viruses, Technology Classifications > Research Tools

A Novel Method for Generating and Screening Peptides and Libraries Displayed on Adenovirus Fiber

C10152: A Novel Method for Generating and Screening Peptides and Libraries Displayed on Adenovirus Fiber Technical Details: Capsid-displayed adenoviral peptide libraries have been a significant yet unfeasible goal in biotechnology. Three barriers have made this difficult: the large size of the viral genome, the low efficiency of converting plasmid-based...

Published: 3/13/2025 | Inventor(s): Ronald Rodriguez, Wasim Chowdhury, Tarana Kudrolli, Shawn Lupold

Keywords(s): Adeno Virus, Basic Research Biomarker, Cloning Reagents, Discovery/Research Tools, Plasmid, Research Reagent, Viruses

Category(s): Technology Classifications > Research Tools > Vectors & Plasmids, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Viruses

IB3-1

C04681: IB3-1 Technical Details: Cystic Fibrosis bronchial epithelial cell line isolated from a patient with genotype ?F508 /W1282X. Cells were immortalized with adeno12SV0.Looking for Partners: This cell line will be useful for the identification of drugs that treat cystic fibrosis.Publications Am J Physiol Cell Physiol. 2000 Feb;278(2):C259-67Sin...

Published: 3/13/2025 | Inventor(s): William Guggino, Pamela Zeitlin

Keywords(s): Adeno Virus, Basic Research Biomarker, Cell Model, Cystic Fibrosis, Cystic Fibrosis (CF), Discovery/Research Tools, Disease Indication, Epithelial Cells, Genetic Disorders, In Vitro Research Tool, Research Reagent, Viruses

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Genetic Diseases > Cystic Fibrosis, Clinical and Disease Specializations > Rare Diseases, Clinical and Disease Specializations > Respiratory Diseases, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Viruses, Clinical and Disease Specializations > Genetic Diseases, Technology Classifications > Research Tools

A Simplified System for Generating Recombinant Adenoviruses

C03356: A Simplified System for Generating Recombinant Adenoviruses Technical Details: Recombinant adenoviruses provide a versatile system for gene expression studies and therapeutic applications. A strategy, which simplifies the generation and production of such viruses is reported here. A recombinant adenoviral plasmid is generated with a minimum...

Published: 3/13/2025 | Inventor(s): Tong-Chuan He, Kenneth Kinzler, Bert Vogelstein

Keywords(s): Adeno Virus, Basic Research Biomarker, Discovery/Research Tools, Disease Indication, Infectious Diseases, Research Reagent, Therapeutic Matter, Therapeutic Substance Synthesis Method, Therapeutics, Viruses

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools > Viruses, Technology Classifications > Therapeutic Modalities, Technology Classifications > Research Tools

W162 Cells, Adenovirus Mutants H5dl1014 and H5dl1014

C03177: W162 Cells, Adenovirus Mutants H5dl1014 and H5dl1014 Technical Details: W162 cells are transformed Vero cells which permit highly efficient plaque formation by deletion mutant adenoviruses. These defective adenoviral deletion mutants (H5dl1011 and H5dl1014) lack coding sequences within the "Early Region 4" (E4). Looking for Partners: Genetic...

Published: 3/13/2025 | Inventor(s): Eileen Bridge, David Weinberg, Gary Ketner

Keywords(s): Adeno Virus, Basic Research Biomarker, Discovery/Research Tools, Research Reagent, Viruses

Category(s): Technology Classifications > Research Tools > Viruses, Technology Classifications > Research Tools